Significant association of high-risk human papillomavirus (HPV) but not of p53 polymorphisms with oral squamous cell carcinomas in Malaysia

• Main Authors: Saini, R., Tang, T.H., Zain, R.B., Cheong, S.C., Musa, K.I., Saini, D., Ismail, A.R., Abraham, M.T., Mustafa, W.M.W., Santhanam, J.
• Format: Article
• Language: English; English
• Published: Springer Verlag (Germany) 2011
• Subjects: Oral surger
• Online Access: http://eprints.um.edu.my/2515/1/HPV.pdf; http://eprints.um.edu.my/2515/2/Significant_association_of_high-risk_human_papillomavirus_%28HPV%29_but_not_of_p53_polymorphisms_with_oral_squamous_cell_carcinomas_in_Malaysia.pdf; http://eprints.um.edu.my/2515/

Purpose: The purpose of this study was to evaluate the role of HPV and p53 polymorphisms in oral squamous cell carcinomas (OSCC) affecting Malaysian population. Methods: We analysed frozen samples from 105 OSCC as well as 105 oral specimens derived from healthy individuals. PCR assays targeting two...