High throughput mutational profiling of signaling molecules in oral cancer

• Main Authors: Zanaruddin, S.N.S., Cheong, S.C., Rahman, Z.A.A., Abd Ghani, W.M.N.W., Mustafa, W.M.W., Zain, R.B., Kong, Y.H., Hor, S.Y., Teo, S.H.
• Format: Article
• Language: English; English
• Published: Elsevier 2011
• Subjects: Oral surger
• Online Access: http://eprints.um.edu.my/2483/1/High_throughput_mutational_profiling_of_signaling_molecules_in_oral_cancer.pdf; http://eprints.um.edu.my/2483/2/rosnah1.pdf; http://eprints.um.edu.my/2483/; https://doi.org/10.1016/j.oraloncology.2011.06.371

It is well established that a plethora of mutations that occur in oncogenes and tumor-suppressor genes are the main drivers of tumorigenesis. The identification of these mutations provides important clues to the cellular processes of carcinogenesis and affords an opportunity for these genes to be us...