Jerantinine B Enhances the Mitochondria-Mediated Apoptosis by p53 Activation in Human Glioblastoma Cells via a Combination with δ-Tocotrienol

• Main Authors: Abubakar, Ibrahim Babangida, Lim, Kuan Hon, Kam, Toh Seok, Loh, Hwei San
• Format: Article
• Published: Taylor & Francis 2018
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/22715/; https://doi.org/10.1080/22311866.2018.1440253

Combined treatment using tocotrienols at low dosage with chemotherapeutic agents has been suggested as an alternative to circumvent the single high-dose associated metabolic degradation and non-selective toxicity of the bioactive compounds. A synergism of combined δ-tocotrienol and jerantinine B in...