Deoxyelephantopin ameliorates lipopolysaccharides (LPS)-induced memory impairments in rats: Evidence for its anti-neuroinflammatory properties

• Main Authors: Andy, Shathiswaran N., Pandy, Vijayapandi, Alias, Zazali, Kadir, Habsah Abdul
• Format: Article
• Published: Elsevier 2018
• Subjects: Q Science (General); QH Natural history; R Medicine
• Online Access: http://eprints.um.edu.my/22473/; https://doi.org/10.1016/j.lfs.2018.05.035

Aim: Neuroinflammation is a critical pathogenic mechanism of most neurodegenerative disorders especially, Alzheimer's disease (AD). Lipopolysaccharides (LPS) are known to induce neuroinflammation which is evident from significant upsurge of pro-inflammatory mediators in in vitro BV-2 microglial...