Optimization of Hydrocortisone-Loaded Nanoemulsion Formulation Using D-Optimal Mixture Design

• Main Authors: Kong, W.Y., Salim, Norazlinaliza, Masoumi, Hamid Reza Fard, Basri, Mahiran, Da Costa, Stephanie S., Ahmad, Noraini
• Format: Article
• Published: Chemic Publishing Company 2018
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/21587/; https://doi.org/10.14233/ajchem.2018.21104

Optimization of hydrocortisone-loaded nanoemulsion formulation was achieved by low energy emulsification method. D-optimal mixture design was used with the variables parameters of Tween-20, lipoid S75, palm kernel oil ester (PKOE) and deionized water towards a response (viscosity). Hydrocortisone, e...