Parametric optimization of polycaprolactone synthesis catalysed by Candida antarctica lipase B using response surface methodology

• Main Authors: Pakalapati, Harshini, Arumugasamy, Senthil Kumar, Jewaratnam, Jegalakshimi, Wong, Yong Jie, Khalid, Mohammad
• Format: Article
• Published: Wiley 2018
• Subjects: TP Chemical technology
• Online Access: http://eprints.um.edu.my/21049/; https://doi.org/10.1002/bip.23240

A statistical approach with D-optimal design was used to optimize the process parameters for polycaprolactone (PCL) synthesis. The variables selected were temperature (50°C-110°C), time (1-7 h), mixing speed (50-500 rpm) and monomer/solvent ratio (1:1-1:6). Molecular weight was chosen as response an...