Early AbobotulinumtoxinA (Dysport®) in Post-Stroke Adult Upper Limb Spasticity: ONTIME Pilot Study

• Main Authors: Rosales, Raymond, Balcaitiene, Jovita, Berard, Hugues, Maisonobe, Pascal, Goh, Khean, Kumthornthip, Witsanu, Mazlan, Mazlina, Abdul Latif, Lydia, Delos Santos, Mary, Chotiyarnwong, Chayaporn, Tanvijit, Phakamas, Nuez, Odessa, Kong, Keng
• Format: Article
• Published: MDPI 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/20873/; https://doi.org/10.3390/toxins10070253

The ONTIME study investigated whether early post-stroke abobotulinumtoxinA injection delays appearance or progression of upper limb spasticity (ULS) symptoms. ONTIME (NCT02321436) was a 28-week, exploratory, double-blind, randomized, placebo-controlled study of abobotulinumtoxinA 500U in patients wi...