Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices
Protein drugs may encounter conformational perturbations during the formulation processing of lipid-based solid dosage forms. In aqueous protein solutions, attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy can investigate these conformational changes following the subtr...
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Main Authors: | Zeeshan, Farrukh, Tabbassum, Misbah, Jorgensen, Lene, Medlicott, Natalie J. |
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Format: | Article |
Published: |
SAGE Publications
2018
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Online Access: | http://eprints.um.edu.my/20176/ https://doi.org/10.1177/0003702817739908 |
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