Cycloartane triterpenoid (23R, 24E)-23-acetoxymangiferonic acid inhibited proliferation and migration in B16-F10 melanoma via MITF downregulation caused by inhibition of both β-catenin and c-Raf–MEK1–ERK signaling axis
We recently reported that (23R, 24E)-23-acetoxymangiferonic acid (23R-AMA), a cycloartane triterpenoid isolated by activity-guided separation from a methanol extract of Garcinia sp. bark, inhibited melanin production via inhibition of tyrosinase (TYR) expression in the B16-F10 melanoma cell line. Si...
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Main Authors: | Kaneda, Toshio, Matsumoto, Misaki, Sotozono, Yayoi, Fukami, Satoshi, Nugroho, Alfarius Eko, Hirasawa, Yusuke, A. Hadi, A. Hamid, Morita, Hiroshi |
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Format: | Article |
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Springer Verlag (Germany)
2019
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Online Access: | http://eprints.um.edu.my/20058/ https://doi.org/10.1007/s11418-018-1233-7 |
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