Synthesis of an anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell line

Anthraquinones are an important class of naturally occurring biologically active compounds. In this study, anthraquinone derivative 1,3-dihydroxy-9,10-anthraquinone-2-carboxylic acid (DHAQC) (2) was synthesized with 32% yield through the Friedel–Crafts condensation reaction. The mechanisms of cytoto...

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Bibliographic Details
Main Authors: Yeap, S.K., Akhtar, M.N., Lim, K.L., Abu, N., Ho, W.Y., Zareen, S., Rohani, K., Ky, H., Tan, S.W., Lajis, N., Alitheen, N.B.
Format: Article
Published: Dove Medical Press 2015
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Online Access:http://eprints.um.edu.my/19383/
http://dx.doi.org/10.2147/DDDT.S65468
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