Kelussia odoratissima Mozaff. activates intrinsic pathway of apoptosis in breast cancer cells associated with S phase cell cycle arrest via involvement of p21/p27 in vitro and in vivo

• Main Authors: Karimian, H., Arya, Aditya, Fadaeinasab, M., Razavi, M., Hajrezaei, M., Khan, A.K., Ali, Hapipah Mohd, Abdulla, Mahmood Ameen, Noordin, M.I.
• Format: Article
• Published: Dove Medical Press 2017
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/19145/; http://dx.doi.org/10.2147/DDDT.S121518

Background: The aim of this study was to evaluate the anticancer potential of Kelussia odoratissima. Several in vitro and in vivo biological assays were applied to explore the direct effect of an extract and bioactive compound of this plant against breast cancer cells and its possible mechanism of a...