Identification of 5-Methoxy-2-(Diformylmethylidene)-3,3-Dimethylindole as an Anti-Influenza A Virus Agent

• Main Authors: Tan, M.C., Wong, W.Y., Ng, W.L., Yeo, K.S., Mohidin, T.B.M., Lim, Y.Y., Lafta, F., Mohd Ali, H., Ea, C.K.
• Format: Article
• Published: Public Library of Science 2017
• Subjects: Q Science (General); QD Chemistry; QH Natural history
• Online Access: http://eprints.um.edu.my/19008/; http://dx.doi.org/10.1371/journal.pone.0170352

Influenza virus is estimated to cause 3-5 million severe complications and about 250-500 thousand deaths per year. Different kinds of anti-influenza virus drugs have been developed. However, the emergence of drug resistant strains has presented a big challenge for efficient antiviral therapy. Indole...