A cell-based screening system for anti-influenza A virus agents

• Main Authors: Wong, W.Y., Loh, S.W., Ng, W.L., Tan, M.C., Yeo, K.S., Looi, C.Y., Maah, M.J., Ea, C.K.
• Format: Article
• Published: Nature Publishing Group 2015
• Subjects: QD Chemistry; QH Natural history; R Medicine
• Online Access: http://eprints.um.edu.my/19434/; http://dx.doi.org/10.1038/srep08672

Emerging of drug resistant influenza A virus (IAV) has been a big challenge for anti-IAV therapy. In this study, we describe a relatively easy and safe cell-based screening system for anti-IAV replication inhibitors using a non-replicative strain of IAV. A nickel (II) complex of polyhydroxybenzaldeh...