Sustained efficacy of artesunate-sulfadoxine-pyrimethamine against Plasmodium falciparum in Yemen and a renewed call for an adjunct single dose primaquine to clear gametocytes

Background: In Yemen, artesunate plus sulfadoxine-pyrimethamine (AS + SP) has been used as first-line treatment for uncomplicated falciparum malaria, which accounts for about 99 % of malaria cases. There is evidence that resistance to SP is increasing, with potential negative impact on efficacy, and...

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Main Authors: Atroosh, W.M., Al-Mekhlafi, H.M., Snounou, G., Al-Jasari, A., Sady, H., Nasr, N.A., Lau, Y.L., Surin, J.
Format: Article
Published: BioMed Central 2016
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Online Access:http://eprints.um.edu.my/18370/
https://doi.org/10.1186/s12936-016-1344-0
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