Polymorphism analysis of pfmdr1 gene in Plasmodium falciparum isolates 11 years post-adoption of artemisinin-based combination therapy in Saudi Arabia

• Main Authors: Al-Mekhlafi, Hesham M., Madkhali, Aymen M., Abdulhaq, Ahmed A., Atroosh, Wahib Mohsen, Ghzwani, Ahmad Hassn, Zain, Khalid Ammash, Ghailan, Khalid Y., Hamali, Hassan A., Mobarki, Abdullah A., Alharazi, Talal H., Eisa, Zaki M., Lau, Yee-Ling
• Format: Article
• Published: Nature Portfolio 2022
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://eprints.um.edu.my/43074/

A total of 227 Plasmodium falciparum isolates from Jazan region, southwestern Saudi Arabia were amplified for the P. falciparum multi-drug resistance 1 (pfmdr1) gene to detect point mutations 11 years after the introduction of artemisinin-based combination therapy (ACT) in Saudi Arabia. The pfmdr1 8...