Evaluation of pharmacokinetics and blood-brain barrier permeability of mitragynine using in vivo microdialysis technique
A microdialysis system coupled with a sensitive ultra-fast liquid chromatography–mass spectrometry (UFLC-MS) method was developed for the pharmacokinetic analysis of mitragynine in rat blood and striatum. Mitragynine is an active alkaloid of Mitragyna speciosa and has been proposed to be used for op...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Published: |
Elsevier
2017
|
| Subjects: | |
| Online Access: | http://eprints.um.edu.my/17613/ http://dx.doi.org/10.1016/j.jpba.2017.05.020 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|