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Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii

A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell g...

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Main Authors: Hirasawa, Y., Shoji, T., Arai, T., Nugroho, A.E., Deguchi, J., Hosoya, T., Uchiyama, N., Goda, Y., Awang, K., Hadi, A.H.A., Shiro, M., Morita, H.
Format: Article
Published: Elsevier 2010
Subjects:
Q Science (General)
Online Access:http://eprints.um.edu.my/14977/
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spelling my.um.eprints.149772015-12-01T00:38:15Z http://eprints.um.edu.my/14977/ Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii Hirasawa, Y. Shoji, T. Arai, T. Nugroho, A.E. Deguchi, J. Hosoya, T. Uchiyama, N. Goda, Y. Awang, K. Hadi, A.H.A. Shiro, M. Morita, H. Q Science (General) A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell growth inhibitory activity against various human cancer cell lines. (C) 2010 Elsevier Ltd. All rights reserved. Elsevier 2010 Article PeerReviewed Hirasawa, Y. and Shoji, T. and Arai, T. and Nugroho, A.E. and Deguchi, J. and Hosoya, T. and Uchiyama, N. and Goda, Y. and Awang, K. and Hadi, A.H.A. and Shiro, M. and Morita, H. (2010) Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii. Bioorganic & Medicinal Chemistry Letters, 20 (6). pp. 2021-2024.
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
spellingShingle Q Science (General)
Hirasawa, Y.
Shoji, T.
Arai, T.
Nugroho, A.E.
Deguchi, J.
Hosoya, T.
Uchiyama, N.
Goda, Y.
Awang, K.
Hadi, A.H.A.
Shiro, M.
Morita, H.
Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
description A new bisindole alkaloid, bisleuconothine A(1) consisting of an eburnane-aspidosperma type skeleton, was isolated from the bark of Leuconotis griffithii. The structure including absolute stereochemistry was elucidated on the basis of 2D NMR data and X-ray analysis. Bisleuconothine A(1) showed cell growth inhibitory activity against various human cancer cell lines. (C) 2010 Elsevier Ltd. All rights reserved.
format Article
author Hirasawa, Y.
Shoji, T.
Arai, T.
Nugroho, A.E.
Deguchi, J.
Hosoya, T.
Uchiyama, N.
Goda, Y.
Awang, K.
Hadi, A.H.A.
Shiro, M.
Morita, H.
author_facet Hirasawa, Y.
Shoji, T.
Arai, T.
Nugroho, A.E.
Deguchi, J.
Hosoya, T.
Uchiyama, N.
Goda, Y.
Awang, K.
Hadi, A.H.A.
Shiro, M.
Morita, H.
author_sort Hirasawa, Y.
title Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_short Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_full Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_fullStr Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_full_unstemmed Bisleuconothine A, an eburnane-aspidosperma bisindole alkaloid from Leuconotis griffithii
title_sort bisleuconothine a, an eburnane-aspidosperma bisindole alkaloid from leuconotis griffithii
publisher Elsevier
publishDate 2010
url http://eprints.um.edu.my/14977/
_version_ 1643689946578419712
score 13.160551

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