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Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis

Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR...

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Main Authors: Gan, Chew Yan, Low, Yun Yee, Robinson, W.T., Komiyama, K., Kam, Toh Seok
Format: Article
Published: Elsevier 2010
Subjects:
Q Science (General)
Online Access:http://eprints.um.edu.my/12666/
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spelling my.um.eprints.126662021-03-22T03:39:05Z http://eprints.um.edu.my/12666/ Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis Gan, Chew Yan Low, Yun Yee Robinson, W.T. Komiyama, K. Kam, Toh Seok Q Science (General) Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells. (C) 2010 Elsevier Ltd. All rights reserved. Elsevier 2010 Article PeerReviewed Gan, Chew Yan and Low, Yun Yee and Robinson, W.T. and Komiyama, K. and Kam, Toh Seok (2010) Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis. Phytochemistry, 71 (11-12). pp. 1365-1370. ISSN 0031-9422
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
spellingShingle Q Science (General)
Gan, Chew Yan
Low, Yun Yee
Robinson, W.T.
Komiyama, K.
Kam, Toh Seok
Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
description Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells. (C) 2010 Elsevier Ltd. All rights reserved.
format Article
author Gan, Chew Yan
Low, Yun Yee
Robinson, W.T.
Komiyama, K.
Kam, Toh Seok
author_facet Gan, Chew Yan
Low, Yun Yee
Robinson, W.T.
Komiyama, K.
Kam, Toh Seok
author_sort Gan, Chew Yan
title Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_short Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_full Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_fullStr Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_full_unstemmed Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_sort aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from leuconotis
publisher Elsevier
publishDate 2010
url http://eprints.um.edu.my/12666/
_version_ 1695531080607596544
score 13.160551

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