Biological determinants of immune reconstitution in HIV-infected patients receiving antiretroviral therapy: The role of interleukin 7 and interleukin 7 receptor alpha and microbial translocatioa

• Main Authors: Rajasuriar, R., Booth, D., Solomon, A., Chua, K., Spelman, T., Gouillou, M., Schlub, T.E., Davenport, M., Crowe, S., Elliott, J., Hoy, J., Fairley, C., Stewart, G., Cameron, P., Lewin, S.R.
• Format: Article
• Published: Elsevier 2010
• Subjects: Q Science (General)
• Online Access: http://eprints.um.edu.my/12170/

Background. Multiple host factors may influence CD4(+) T cell reconstitution in human immunodeficiency virus (HIV)-infected patients after suppressive antiretroviral therapy (ART). We hypothesized that residual immune activation and polymorphisms in the interleukin 7 (IL-7) receptor alpha (IL-7R alp...