The optimal mixture design of experiments: Alternative method in optimizing the aqueous phase composition of a microemulsion

• Main Authors: Jeirani, Z., Mohamed Jan, B., Si Ali, B., Noor, I.M., See, C.H., Saphanuchart, W.
• Format: Article
• Published: Elsevier 2012
• Subjects: T Technology (General); TA Engineering (General). Civil engineering (General); TP Chemical technology
• Online Access: http://eprints.um.edu.my/11969/; http://www.sciencedirect.com/science/article/pii/S0169743911002127; http://dx.doi.org/10.1016/j.chemolab.2011.10.008

In this paper, an optimum mixture Design of Experiment (DOE) method was used to determine the optimum aqueous phase formulation of a microemulsion. Based on the Design Expert software, a quadratic model was established as a function of the microemulsion component fractions. The model was validated e...