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Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis

Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR...

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Main Authors: Kam, Toh Seok, Gan, C.Y., Low, Y.Y., Robinson, W.T., Komiyama, K.
Format: Article
Language:English
Published: Elsevier 2010
Subjects:
QD Chemistry
Online Access:http://eprints.um.edu.my/10406/1/Aspidospermatan%E2%80%93aspidospermatan_and_eburnane-sarpagine_bisindole_alkaloids_from_Leuconotis.pdf
http://eprints.um.edu.my/10406/
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spelling my.um.eprints.104062021-03-22T03:38:13Z http://eprints.um.edu.my/10406/ Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis Kam, Toh Seok Gan, C.Y. Low, Y.Y. Robinson, W.T. Komiyama, K. QD Chemistry Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells. Elsevier 2010 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10406/1/Aspidospermatan%E2%80%93aspidospermatan_and_eburnane-sarpagine_bisindole_alkaloids_from_Leuconotis.pdf Kam, Toh Seok and Gan, C.Y. and Low, Y.Y. and Robinson, W.T. and Komiyama, K. (2010) Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis. Phytochemistry, 71. pp. 1365-1370. ISSN 0031-9422 doi:10.1016/j.phytochem.2010.05.015
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic QD Chemistry
spellingShingle QD Chemistry
Kam, Toh Seok
Gan, C.Y.
Low, Y.Y.
Robinson, W.T.
Komiyama, K.
Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
description Leucofoline and leuconoline, representing the first members of the aspidospermatan–aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells.
format Article
author Kam, Toh Seok
Gan, C.Y.
Low, Y.Y.
Robinson, W.T.
Komiyama, K.
author_facet Kam, Toh Seok
Gan, C.Y.
Low, Y.Y.
Robinson, W.T.
Komiyama, K.
author_sort Kam, Toh Seok
title Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_short Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_full Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_fullStr Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_full_unstemmed Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
title_sort aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from leuconotis
publisher Elsevier
publishDate 2010
url http://eprints.um.edu.my/10406/1/Aspidospermatan%E2%80%93aspidospermatan_and_eburnane-sarpagine_bisindole_alkaloids_from_Leuconotis.pdf
http://eprints.um.edu.my/10406/
_version_ 1695531080324481024
score 13.160551

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