Development of humanized monoclonal antibody by logical approach: characterization, functional studies in vitro and immunogenicity studies in vivo in non-human primates
Monoclonal antibodies (mAbs) are widely used due to their exquisite specificity and once were hailed as the solution to cancer. However, when mouse mAbs are administered in humans, anti-antibody response (AAR) is frequently observed. Using humanized mAbs which are commonly developed by CDR-grafting...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Academic Journals
2012
|
| Subjects: | |
| Online Access: | http://eprints.um.edu.my/10074/1/Development_of_humanized_monoclonal_antibody_by_logical_approach.pdf http://eprints.um.edu.my/10074/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|