Comments: Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways.

Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways.

Centratherum anthelminticum (L.) Kuntze (scientific synonyms: Vernonia anthelmintica; black cumin) is one of the ingredients of an Ayurvedic preparation, called “Kayakalp”, commonly applied to treat skin disorders in India and Southeast Asia. Despite its well known anti-inflammatory property on skin...

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Bibliographic Details
Main Author:	Leong, K.H.
Format:	Article
Language:	English
Published:	BioMed Central 2013
Subjects:	Q Science (General) QD Chemistry QH301 Biology QK Botany R Medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology RS Pharmacy and materia medica RV Botanic, Thomsonian, and eclectic medicine
Online Access:	http://eprints.um.edu.my/10003/1/Induction_of_apoptosis_in_melanoma_A375_cells_by_a_chloroform_fraction_of_Centratherum_anthelminticum_L._seeds.pdf http://eprints.um.edu.my/10003/ http://www.biomedcentral.com/1472-6882/13/166
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Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways.

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