Cytotoxicity of oxidised Low Density Lipoprotein (OxLDL) on U937 cells: a comparison of viability measurement by propidium iodide-flow cytometry and MTT reduction assays / Mohd Izani Othman, Steven Gieseg and Barry Hock

• Main Authors: Othman, Mohd Izani, Gieseg, Steven, Hock, Barry
• Format: Article
• Language: English
• Published: 2016
• Subjects: Medical education. Medical schools. Research; Biomedical engineering
• Online Access: https://ir.uitm.edu.my/id/eprint/83019/1/83019.pdf; https://ir.uitm.edu.my/id/eprint/83019/; https://e-ajuitmct.uitm.edu.my/v3/

Atherosclerosis is a major cause of cardiovascular disease. It is characterised by a development of atherosclerotic plaque in a blood vessel wall that involves a death of macrophages. Oxidized low density lipoprotein (oxLDL) is a toxic and a key player that promotes macrophages recruitment, activati...