Hit to lead: unravelling the potential of flavonoids as multi-subtypes phosphodiesterase (PDE) inhibitors / Muhd Hanis Md Idris

• Main Author: Md Idris, Muhd Hanis
• Format: Thesis
• Language: English
• Published: 2021
• Subjects: Medical technology; Biomedical engineering
• Online Access: https://ir.uitm.edu.my/id/eprint/53622/1/53622.PDF; https://ir.uitm.edu.my/id/eprint/53622/

Drug discovery is a lengthy process that requires a lot of resources and investment. Using computational approach, the time and the cost of drug development could be reduced. Drug candidates that fail to go into market due to unfavourable pharmacokinetic profiles and toxicity could be decreased. Cha...