Targeted delivery of BDNF-loaded poly (lactide-co-glycolide) nanoparticle to the brain: penetration through blood brain barrier and neuroprotective effect in stroke / Siti Norsyafika Kamarudin

• Main Author: Kamarudin, Siti Norsyafika
• Format: Thesis
• Language: English
• Published: 2019
• Subjects: RM Therapeutics. Pharmacology; Administration
• Online Access: https://ir.uitm.edu.my/id/eprint/28309/1/28309.pdf; https://ir.uitm.edu.my/id/eprint/28309/

Stroke remains a major public health burden in Malaysia due to high morbidity and mortality. Neuroprotection by Brain derived neurotrophic factor (BDNF) has the potential to minimise the ischemic damage and theoretically improve freedom from disability among stroke survivors. There is a need to deve...