Genetic polymorphism of drug metabolizing enzymes and estrogen receptor in pharmacogenetics of tamoxifen: implication for optimization of breast cancer treatment / Teh Lay Kek and Mohd Zaki Salleh
Introduction: Tamoxifen has been used as a hormonal therapy in breast cancer patients who are positive for estrogen receptor. The drug is metabolized by Cytochrome P450 2D6 (CYP2D6) into several metabolite. Variation in CYP2D6 activity has important therapeutic consequences and can play a significan...
Saved in:
Main Authors: | Lay Kek, Teh, Salleh, Mohd Zaki |
---|---|
Format: | Research Reports |
Language: | English |
Published: |
Research Management Institute (RMI)
2010
|
Subjects: | |
Online Access: | http://ir.uitm.edu.my/id/eprint/24806/1/LP_TEH%20LAY%20KEK%20RMI%2010_5.pdf http://ir.uitm.edu.my/id/eprint/24806/ |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tacrolimus pharmacogenetics: the influence of genetic polymorphisms of CYP3A5, MDRl and Pregnane X Receptor (PXR) in transplant patients / Professor Dr. Mohd Zaki Salleh and Associate Prof. Dr Teh Lay Kek
by: Salleh, Mohd Zaki, et al.
Published: (2010) -
Cancerpharmacogenomics: the relevance of genetic
profile in optimization drug therapy for azathiopurine and
5-Fluorouracil / Teh Lay Kek And Mohd Zaki Salleh
by: Teh, Lay Kek, et al.
Published: (2010) -
Evaluation of the VKORC1 haplotypes in individualising warfarin therapy / Mohd Zaki Salleh, Teh Lay Kek and Fazleen Haslinda Mohd Hatta
by: Salleh, Mohd Zaki, et al.
Published: (2010) -
Unraveling of the genetic polymorphism for ultra-rapid metabolism of phenytoin / Fazleen Haslinda Mohd Hatta , Prof Madya Dr The Lay Kek , Prof Dr Mohd Zaki Salleh
by: Mohd Hatta, Fazleen Haslinda, et al.
Published: (2010) -
Cancer pharmacogenomics: the relevance of genetic profile in optimization drug therapy for azathiopurine and 5-fluorouracil / Prof Madya Dr Teh Lay Kek and Prof Dr Mohd Zaki Salleh
by: Teh, Lay Kek, et al.
Published: (2010)