A novel gene-activated matrix composed of PEI/plasmid-BMP2 complexes and hydroxyapatite/chitosan-microspheres promotes bone regeneration

The incorporation of pro-osteogenic growth factors into bone graft materials to enhance bone regeneration is a key research area within the field of bone tissue engineering and regenerative medicine. However, growth factors directly incorporated in protein form are easily degraded, and have a limite...

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Main Authors: Ding, Ruyuan, Liu, Yajun, Cheng, Dawei, Yang, Gang, Wu, Wenjing, Du, Haoran, Jin, Xin, Chen, Yihan, Wang, Yuanyin, Heng, Boon Chin *, Xu, Jianguang
Format: Article
Published: Springer 2022
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Online Access:http://eprints.sunway.edu.my/3114/
https://link.springer.com/article/10.1007/s12274-022-4292-8
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