Is Proteolytic Cleavage Essential for the Enhanced Activity of Hydra Pore-Forming Toxin, HALT-4?

Hydra actinoporin-like toxin 4 (HALT-4) differs from other actinoporins due to its N-terminal propart that contains approximately 103 additional residues. Within this region, we identified five dibasic residues and assumed that, when cleaved, they could potentially exhibit HALT-4's cytolytic ac...

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Bibliographic Details
Main Authors: Yap, Wei Yuen *, Hwang, Jung Shan *
Format: Article
Language:English
Published: MDPI 2023
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Online Access:http://eprints.sunway.edu.my/2718/1/Hwang%20Jung%20Shan_Is%20proteolytic%20cleavage%20essential.pdf
http://eprints.sunway.edu.my/2718/
https://doi.org/10.3390/toxins15060396
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