QSAR modelling to predict structural features of certain sulfonamide as Urokinase-type Plasminogen Activator inhibitors
The serine hydrolase family includes serine proteases. It is essential for hydrolyzing protein peptide bonds and breaking them. The urokinase-type plasminogen activator (uPA) selectively binds to the uPAR on numerous cell types, including cancer cells. Pericellular proteolysis of cell-bound proteins...
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Main Authors: | Jawarkar, Rahul D, Zaki, Magdi E A, Al-Hussain, Sami, Alzahrani, Abdullah Yahya Abdullah, Long, Chiau Ming *, Samad, Abdul, Ingle, Rahul G., Mali, Suraj N. |
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Format: | Article |
Published: |
Elsevier
2024
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Online Access: | http://eprints.sunway.edu.my/2611/ https://doi.org/10.1016/j.chphi.2024.100544 |
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