Quantitative description of publications (1986-2020) related to Alzheimer disease and oxidative stress: a bibliometric study
While the pathological mechanism of Alzheimer’s Disease (AD) is unclear, oxidative stress has been proposed to be one of its related theories, which can help to uncover the disease’s pathological factors. This review aims to provide a quantitative description and data visualisation of AD and ox...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hücresel Sinir Bilimleri ve Oksidatif Stres Derneği
2021
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/93046/8/93046_Quantitative%20description%20of%20publications%20%281986-2020%29.pdf http://irep.iium.edu.my/93046/ https://dergipark.org.tr/en/download/article-file/1802910 |
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| Summary: | While the pathological mechanism of Alzheimer’s
Disease (AD) is unclear, oxidative stress has been
proposed to be one of its related theories, which can help
to uncover the disease’s pathological factors. This review
aims to provide a quantitative description and data
visualisation of AD and oxidative stress research from the
literature obtained from the Scopus database. Based on
the keywords used, which are related to AD and oxidative
stress in the article title, 996 documents were retrieved for
further analysis. Microsoft Excel, VOSviewer and
Harzing’s Publish or Perish were used to conduct the
frequency analysis, data visualisation, and citation
analysis. There is a continuous growth in the number of
publications on research in AD and oxidative stress,
starting from 1986 and spanning 35 years. The most cited
article was “Oxidative stress hypothesis in Alzheimer's
disease”. The Journal of Alzheimer Disease published the
most number of publications related to AD and oxidative
stress, while the United States and its institutions were the
main contributors. Our findings suggest that research on aetiopathology, biomarkers and neuroprotective agents
for AD dominated this research field. Our bibliometric analysis provides distinct trends in AD and oxidative stress research in the last 35 years. Our findings highlight current hot topics related to biomarkers for screening and diagnosis of AD as well as neuroprotective agents used as disease-modifying
therapies of AD |
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