Evaluation of high resolution melting technique for detection of JAK2-V617F mutation in formalin-fixed paraffin-embedded specimen from myeloproliferative neoplasm cases

• Main Authors: Abdullahi, Mohammad Reza, Abdullah, Nor Zamzila, Ismail, Rosmawati, Muhammad, Siti Aeshah @ Naznin, A.Talib, Norlelawati
• Format: Article
• Language: English; English
• Published: Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia 2019
• Subjects: R Medicine (General); RB Pathology
• Online Access: http://irep.iium.edu.my/76120/1/76120_Evaluation%20of%20high%20resolution%20melting%20technique%20for%20detection%20of%20JAK2-V617F%20mutation%20in%20formalin-fixed%20paraffin-embedded%20specimen%20from%20myeloproliferative%20neoplasm%20cases.pdf; http://irep.iium.edu.my/76120/2/76120_Evaluation%20of%20high%20resolution%20melting%20technique%20for%20detection%20of%20JAK2-V617F%20mutation%20in%20formalin-fixed%20paraffin-embedded%20specimen%20from%20myeloproliferative%20neoplasm%20case_SCOPUS.pdf; http://irep.iium.edu.my/76120/; http://iiumedic.net/imjm/v1/download/volume_18_no_2/Pages-from-IMJMVol18No2-15.pdf

Introduction: Myeloproliferative neoplasm (MPN) is a group of myeloid disorders which leads to erythrocytosis, thrombocytosis and leucocytosis. MPN with BCR-ABL positive is chronic myeloid leukaemia (CML) while BCR-ABL negative MPN includes polycythaemia Vera (PV), essential thrombocytemia (ET) an...