Development of alpha mangostin-PLGA nanoparticles as an anticancer agent

• Main Authors: Aimen, Abdo, Mohamed, Farahidah, Bakhtiar, M. Taher
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2011
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/8785/1/Abstract_Dr._Taher-IHCI2011_8785.pdf; http://irep.iium.edu.my/8785/3/mangosteen-IHCI_poster_after_correct_.pdf; http://irep.iium.edu.my/8785/

α-Mangostin, a xanthone which was isolated from Garcinia malaccensis has been documented to exhibit anticancer effects against many cancerous cell lines. Due its high cytotoxicity, this study had attempted to encapsulate the α-mangostin into biodegradable PLGA copolymer using colloidal-extraction so...