Loading celecoxib into solid lipid nanoparticles significantly enhanced the anticancer activity

• Main Authors: Alajami, Hamdan, Fouad, Ehab, Ashour, Abdelkader Elbadawy Abbas, Kumar, Ashok, Yassin, Alaa Eldeen
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2018
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/68827/1/68827_Loading%20celecoxib%20into%20solid%20lipid%20nanoparticles%20significantly%20enhanced%20the%20anticancer%20activity.pdf; http://irep.iium.edu.my/68827/2/final_program.pdf; http://irep.iium.edu.my/68827/; https://2018.controlledreleasesociety.org/

Introduction: Celecoxib (CXB), COX-2 enzyme inhibitor, has been approved recently for the treatment of colorectal polyps. Solid lipid nanoparticles (SLN) have turned out to be an attractive carrier alternative to liposomes and polymeric nanoparticles due to superior stability and biocompatibility. T...