Mechanisms of neuroblastoma cell growth inhibition by CARP-1 functional mimetics.

• Main Authors: Muthu, Magesh, Cheriyan, Vino T., Munie, Sara, Levi, Edi, Frank, John, Ashour, Abdelkader Elbadawy Abbas, Singh, Mandip, Rishi, Arun K.
• Format: Article
• Language: English; English
• Published: The Public Library of Science 2014
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/67281/1/Mechanisms%20of%20Neuroblastoma%20Cell%20Growth%20Inhibition%20by%20CARP-1%20Functional%20Mimetics.pdf; http://irep.iium.edu.my/67281/7/67281_Scopus%20-%20Document%20details.pdf; http://irep.iium.edu.my/67281/; https://journals.plos.org/plosone/s/journal-information

Neuroblastomas (NBs) are a clinically heterogeneous group of extra cranial pediatric tumors. Patients with high-risk, metastatic NBs have a long-term survival rate of below 40%, and are often resistant to current therapeutic modalities. Due to toxic side effects associated with radiation and chemoth...