Identification and testing of novel CARP-1 functional mimetic compounds as inhibitors of non-small cell lung and triple negative breast cancers

• Main Authors: Muthu, Magesh, Somagoni, Jaganmohan, Cheriyan, Vino T., Munie, Sara, Levi, Edi, Ashour, Abdelkader Elbadawy Abbas, Yassin, Alaa Eldeen B., Alafeefy, Ahmed M., Sochacki, Paula, Polin, Lisa A., Reddy, Kaladhar B., Larsen, Scott D., Singh, Mandip, Rishi, Arun K.
• Format: Article
• Language: English
• Published: American Scientific Publishers 2015
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/64285/1/Identification%20and%20Testing%20of%20Novel%20CARP-1%20Functional%20Mimetic%20Compounds%20as%20Inhibitors%20of%20Non-Small%20Cell%20Lung%20and%20Triple%20Negative%20Breast%20Cancers.pdf; http://irep.iium.edu.my/64285/; http://www.ingentaconnect.com/content/asp/jbn/2015/00000011/00000009/art00008

The triple negative breast cancer (TNBCs) and non-small cell lung cancers (NSCLCs) often acquire mutations that contribute to failure of drugs in clinic and poor prognosis, thus presenting an urgent need to develop new and improved therapeutic modalities. Here we report that CARP-1 functional mimeti...