Mechanisms of disordered neurodegenerative function: concepts and facts about the different roles of the protein kinase RNA-like endoplasmic reticulum kinase (PERK)

• Main Authors: Taalab, Yasmeen M., Ibrahim, Nour, Maher, Ahmed, Hassan, Mubashir, Mohammad, Wael, Moustafa, Ahmed A., Salama, Mohamed M., Johar, Dina R., Bernstein, Larry H.
• Format: Article
• Language: English; English; English
• Published: De Gruyter 2018
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/61339/13/61339_Mechanisms%20of%20disordered%20neurodegenerative%20function.pdf; http://irep.iium.edu.my/61339/14/61339_Mechanisms%20of%20disordered%20neurodegenerative%20function_SCOPUS.pdf; http://irep.iium.edu.my/61339/15/61339_Mechanisms%20of%20disordered%20neurodegenerative%20function_WoS.pdf; http://irep.iium.edu.my/61339/; https://www.degruyter.com/view/j/revneuro.ahead-of-print/revneuro-2017-0071/revneuro-2017-0071.xml?format=INT

Neurodegenerative diseases, such as Alzheimer's disease, Huntington's disease, Parkinson's disease, prion disease, and amyotrophic lateral sclerosis, are a dissimilar group of disorders that share a hallmark feature of accumulation of abnormal intraneuronal or extraneuronal misfolded/...