Investigating the potential of Nigella Sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure to cyclophosphamide

• Main Authors: Abdul Rahman, Suzanah, Abdul Samat, Nadia Hanis, Ahmad, Nur Amalina, Abdullah, 'Afif Raihan, Mohd Zahri, Syazana, Kamarzaman, Saheera
• Format: Article
• Language: English; English; English
• Published: Kulliyyah of Medicine, International Islamic University Malaysia 2017
• Subjects: RG Gynecology and obstetrics; RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/58232/1/IMJM-Vol-16-p099-106.pdf; http://irep.iium.edu.my/58232/7/58232-Investigating%20the%20Potential%20of%20Nigella%20Sativa_SCOPUS.pdf; http://irep.iium.edu.my/58232/8/58232-Investigating%20the%20Potential%20of%20Nigella%20Sativa_WOS.pdf; http://irep.iium.edu.my/58232/; http://journals.iium.edu.my/imjm/index.php/eimj/index

Background: Exposure to cyclophosphamide (CPA) during chemotherapy results in over-production of reactive oxygen species and oxidative stress thus causing sperm defects following disturbance to the genetic material of male germ cells. The goal of this study is to assess the potential effects of Nige...