Relationship of brain derived neurotrophic factor DNA methylation with psychopathologic symptoms and antipsychotics in stable schizophrenia

• Main Authors: Abd. Rahim, Nour El Huda, Rahim, Mohd Nabil Fikri, Ku Zaifah, Norsidah, Mohd Noor, Hanisah, Abdullah, Kartini, A.Talib, Norlelawati
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2016
• Subjects: R Medicine (General); RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
• Online Access: http://irep.iium.edu.my/52019/1/Poster%20MSPP%20Huda%20print.pdf; http://irep.iium.edu.my/52019/7/52019_abstract.pdf; http://irep.iium.edu.my/52019/; http://primanexus.com.my/sites/default/files/MSPP_2016_ABSTRACT_BOOK.pdf

Introduction: Brain derived neurotrophic factor (BDNF) contributes to dopamine neurotransmission by supporting the survival and differentiation of the neurons. During epigenetic event, methylated BDNF gene may cause reduction of its expression thus contribute to the clinical presentation and treatme...