Association between LRRTM1 gene DNA methylation and schizophrenia psychopathology

• Main Authors: Abdull Jalil, Mohd Asyraf, Abd Rahim, Nour El Huda, Mohd Noor, Hanisah, Ku Zaifah, Norsidah, A. Talib, Norlelawati
• Format: Conference or Workshop Item
• Language: English; English; English
• Published: 2021
• Subjects: R Medicine (General); RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
• Online Access: http://irep.iium.edu.my/95799/1/6MRS2021%20Abstract%20-%20Oral%20-%20Mohd%20Asyraf%20-%20LRRTM1%20Schizophrenia.pdf; http://irep.iium.edu.my/95799/3/MRS-2021-Abstract-Book-.pdf; http://irep.iium.edu.my/95799/19/Association%20between%20LRRTM1%20gene%20DNA%20methylation%20and%20schizophrenia%20%28new2%29.pdf; http://irep.iium.edu.my/95799/

Introduction: Leucine-rich-repeat transmembrane neuronal protein 1 (LRRTM1) is a synaptic adhesion molecule involved in synapse organization. DNA hypomethylation of the LRRTM1 gene promoter was shown to be associated with familial schizophrenia. However, the association with schizophrenia in general...