Hyaluronidase inhibitory activity of Pentacylic triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, synthesis and QSAR study

The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified...

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Bibliographic Details
Main Authors: Abdullah, Nor Hayati, Thomas, Noel Francis, Sivasothy, Yasodha, Lee, Vannajan Sanghiran, Liew, Sook Yee, Noorbatcha, Ibrahim Ali, Awang , Khalijah
Format: Article
Language:English
Published: MDPI 2016
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Online Access:http://irep.iium.edu.my/49229/1/ijms-17-00143.pdf
http://irep.iium.edu.my/49229/
http://www.mdpi.com/1422-0067/17/2/143
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