Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controlled trial of continuous infusion versus intermittent bolus administration

• Main Authors: Jamal, Janattul-Ain, Roberts, Darren M., Udy, Andrew A, Mat Nor, Mohd Basri, Mohamad Nor, Fariz Safhan, Wallis, Steven C, Lipman, Jeffrey, Roberts, Jason A.
• Format: Article
• Language: English; English
• Published: Elsevier 2015
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/43883/1/Pharmacokinetics_of_piperacillin_in_critically_ill_patients_receiving_continuous_venovenous_haemofiltration_A_randomised_controlled_trial_of_continuous_infusion_versus_intermi.pdf; http://irep.iium.edu.my/43883/4/43883_Pharmacokinetics%20of%20piperacillin%20in%20critically%20ill%20patients%20receiving%20continuous%20venovenous%20haemofiltration_SCOPUS.pdf; http://irep.iium.edu.my/43883/; http://www.sciencedirect.com/science/article/pii/S0924857915001089

Here we describe the pharmacokinetics of piperacillin administered by continuous infusion (CI) versus intermittent bolus (IB) dosing in critically ill patients receiving continuous venovenous haemofiltration (CVVH) and compare the frequency of pharmacodynamic/pharmacokin...