Metabolomics and pharmacogenetics based 5-fluorouracil monitoring in colorectal cancer patients

• Main Authors: Zakaria, Bannur, Mohd Zaki, Salleh, Hashim, Hazwanie, Tom, Hennessy, Md Nor, Azmi, MH, Zailani, Prabu, Ramasamy, ZA, Zakaria, Suneet, S, Ngow, Harris Abdullah, Henry, Guy M., Teh, Laykek
• Format: Article
• Language: English; English
• Published: International Journal of Pharmacy and Pharmaceutical Sciences ( IJPPS) 2014
• Subjects: RC Internal medicine
• Online Access: http://irep.iium.edu.my/42698/1/metabolomics_and_pharmacogenetics_based_5-fluorouracil_monitoring_in_colorectal_cancer_patients.pdf; http://irep.iium.edu.my/42698/4/42698_METABOLOMICS_scopus.pdf; http://irep.iium.edu.my/42698/; http://www.ijppsjournal.com/contents.htm

Objective: To provide quick and accurate clinical diagnostic tools those are currently not available leading to improper management of colorectal cancer (CRC) patients. Methods: The metabolomic profiles of 10 CRC patients treated with 5-fluorouracil and 24 healthy volunteers were analysed. The subje...