Alpha-mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPAR gamma, GLUT4, and leptin expressions

• Main Authors: Bakhtiar, M. Taher, Mohamed Amiroudine, Mohamed Zaffar Ali, Tengku Zakaria, Tengku Muhamad Faris Syafiq, Darnis, Deny Susanti, Arief Ichwan, Solachuddin Jauhari, Kaderi, Mohd Arifin, Ahmed, Qamar Uddin, Zakaria, Zainul Amiruddin
• Format: Article
• Language: English; English; English
• Published: Hindawi Publishing Corporation 2015
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/42492/1/Alpha_mangostin_ECAM.pdf; http://irep.iium.edu.my/42492/4/42492_Alpha-mangostin%20improves%20glucose%20uptake%20and%20inhibits_Scopus.pdf; http://irep.iium.edu.my/42492/5/42492_Alpha-mangostin%20improves%20glucose%20uptake%20and%20inhibits_WOS.pdf; http://irep.iium.edu.my/42492/; https://www.hindawi.com/journals/ecam/2015/740238/

Obesity has been often associated with the occurrence of cardiovascular diseases, type 2 diabetes, and cancer. The development of obesity is also accompanied by significant differentiation of preadipocytes into adipocytes. In this study, we investigated the activity of alpha-mangostin, a major xanth...