Daily Clinical Dose (D) poorly predicts trough serum methadone concentration (C trough) in patients undergo methadone maintenance therapy with good adherence

• Main Authors: Mohamed Nazar, Nor Ilyani, Sim , Hann Liang, Tan, Soo Choon, Ismail, Rusli, Musa, Ramli, Abu Bakar, Ahmad Zafri
• Format: Article
• Language: English
• Published: R. S. Publication 2014
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/36708/1/article_1.pdf; http://irep.iium.edu.my/36708/; http://rspublication.com/ijphc/2014/april14/23.pdf

Methadone maintenance therapy (MMT) has been used for opioid dependence as one of the harm-reduction approaches. It is also effective indirectly to prevent the wide spread of HIV-related risks such as needle sharing behaviour and illicit drug use. With low costs calculated per patient, MMT has been...