Variability of plasma methadone concentration in opiate dependents receiving methadone: a personalised approach towards optimizing dose

• Main Authors: Mohamad, Nasir, Ismail, Rusli, Mohamed Nazar, Nor Ilyani, Tan, Soo Choon, Sim, Hann Liang, Idrus, Ilya Irinaz, Abu Bakar, Nor Hidayah
• Format: Book Chapter
• Language: English
• Published: Intechopen.com 2012
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/35714/1/variability.pdf; http://irep.iium.edu.my/35714/; http://www.intechopen.com/books/toxicity-and-drug-testing/variability-of-plasma-methadone-concentration-in-opiate-dependent-receiving-methadone-a-personalised

1. Introduction 1.1 Methadone and methadone maintenance therapy (MMT): An overview Methadone acts on the opioid receptors and produces many of the same effects of morphine and heroin. In the treatment of opioid dependence, methadone has cross-tolerance with other opioid, including heroin and mor...