QSAR study of flavonoids as platelet-activating factor (PAF) receptor binding antagonists

• Main Authors: Abdullah, Nor Hayati, Kiong, Ling Sui, Noorbatcha, Ibrahim Ali
• Format: Article
• Language: English; English
• Published: AENSI Publications 2014
• Subjects: TP Chemical technology; TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/36396/1/36396_QSAR%20study%20of%20flavonoids%20as%20platelet-activating.pdf; http://irep.iium.edu.my/36396/2/36396_QSAR%20study%20of%20flavonoids%20as%20platelet-activating_SCOPUS.pdf; http://irep.iium.edu.my/36396/; http://www.aensiweb.com/aeb_Special_2014.html

Flavonoids are natural inhibitors against platelet activating factor (PAF) receptor. PAF is involved in several patho-physiological conditions such as inflammation, atherosclerosis, asthma and thrombosis. The PAF actions can be inhibited by blocking its receptor with an antagonist. The aim of this...