Reactive oxygen species and aldehyde dehydrogenase activity in Hodgkin lymphoma cells

• Main Authors: Ikeda, Jun-ichiro, Mamat, Suhana, Tian, Tian, Wang, Yi, Luo, Wenjuan, Rahadiani, Nur, Aozasa, Katsuyuki, Morii, Eiichi
• Format: Article
• Language: English
• Published: Nature Publishing Group 2012
• Subjects: RB Pathology
• Online Access: http://irep.iium.edu.my/34103/1/2012.pdf; http://irep.iium.edu.my/34103/

Tumor cells with tumorigenic potential might be limited to a small population of cells, called cancer-initiating cells (CICs). CICs efficiently form colonies in vitro, yield both CIC and non-CIC populations, maintain reactive oxygen species (ROS) at low levels, show high aldehyde dehydrogenase (ALDH...