Clinical pharmacokinetics and pharmacodynamics of mycophenolate in patients with autoimmune disease

• Main Authors: Abd. Rahman, Nurul Azrin, Tett, Susan E., Staatz, Christian E.
• Format: Article
• Language: English
• Published: Springer International Publishing AG 2013
• Subjects: R Medicine (General); RM Therapeutics. Pharmacology; RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/30553/1/Azrin_AbdRahman_2013.pdf; http://irep.iium.edu.my/30553/; http://link.springer.com/article/10.1007%2Fs40262-013-0039-8

Mycophenolic acid (MPA), the active drug moiety of mycophenolate, is a potent immunosuppressant agent, which is increasingly being used in the treatment of patients with various autoimmune diseases. An understanding of the pharmacokinetics and pharmacodynamics of mycophenolate in this population sho...