Continuous beta-lactam infusion in critically ill patients: the clinical evidence

• Main Authors: Abdul Aziz, Mohd. Hafiz, Dulhunty, Joel M., Bellomo, Rinaldo, Lipman, Jeffrey, Roberts, Jason A.
• Format: Article
• Language: English
• Published: Springer-Verlag Berlin Heidelberg 2012
• Subjects: R Medicine (General); RM Therapeutics. Pharmacology; RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/30503/2/2110-5820-2-37.pdf; http://irep.iium.edu.my/30503/; http://link.springer.com/article/10.1186%2F2110-5820-2-37

There is controversy over whether traditional intermittent bolus dosing or continuous infusion of beta-lactam antibiotics is preferable in critically ill patients. No significant difference between these two dosing strategies in terms of patient outcomes has been shown yet. This is despite compellin...